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Nzoner's Game Room>***NON-POLITICAL COVID-19 Discussion Thread***
JakeF 10:28 PM 02-26-2020
A couple of reminders...

Originally Posted by Bwana:
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
Originally Posted by Dartgod:
People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

[Reply]
Donger 12:03 PM 12-08-2021
For whatever reason, Oregon seems to be doing probably the best reporting on breakthroughs and results:

https://www.google.com/url?sa=t&rct=...64yU46SmEZGhha

During the week of November 21–November 27, there were 4,134 cases of COVID-19. 2,948 (71.3%)were unvaccinated and 1,186 (28.7%) were vaccine breakthrough cases. The median age of breakthrough cases was 45 years. 28 (2.4%) breakthrough cases were residents of care facilities, senior living communities or other congregate living settings. 234 (19.7%) cases were 65 or older. There were 45 (3.8%) cases aged 12-17.
[Reply]
jdubya 12:32 PM 12-08-2021
Originally Posted by Chris Meck:
If not getting the surgery can somehow kill other people, then sure.

The really frustrating part of this whole thing is that it's NOT ABOUT YOU.

It's about spreading it to other people who might die.

If everybody who CAN get the shot gets the shot, then this is the flu.

And I could get back to my life.
The only one not letting you get back to your life is.....you and your local officials. .....not me
[Reply]
Marcellus 01:26 PM 12-08-2021
Originally Posted by Chris Meck:
If not getting the surgery can somehow kill other people, then sure.

The really frustrating part of this whole thing is that it's NOT ABOUT YOU.

It's about spreading it to other people who might die.

If everybody who CAN get the shot gets the shot, then this is the flu.

And I could get back to my life.
Is this the we must protect the vaccinated from the unvaccinated speech?
[Reply]
OnTheWarpath15 02:41 PM 12-08-2021
Update: He's not getting better, and it's likely he goes on a vent soon. So likely that the doc bent some rules and allowed myself and my sisters to visit this morning. Mom still has two days of quarantine before she can go.

I know this might be skirting - or flat blowing over the line - so if I'm in the wrong here, just delete the rest of this mods, but...

This all could have been avoided, but like so many others, he thought information from Facebook/The Internet carries more weight than from fucking professionals.

I hope those of you who are vaxxed and reading this realize how important getting those shots were to you and your families.

And I hope those of you who aren't vaxxed (and can be safely) will reconsider. My stepdad realizes now that he made a huge mistake, and now it's too late.

Don't do this to your families. Get the goddamn shots. Please.
[Reply]
Bugeater 02:57 PM 12-08-2021
Ugh...I am sorry to hear that...shit is all hitting close to home this fall.



And anyone is free to voice opinions in here, the ones I booted earlier were repeatedly blowing up the thread with the same bullshit time and time and time again.
[Reply]
Bearcat 03:29 PM 12-08-2021
Best of luck to your stepdad and family, OTWP.
[Reply]
Rain Man 04:16 PM 12-08-2021
Originally Posted by Bugeater:
Ugh...I am sorry to hear that...shit is all hitting close to home this fall.

....

I'm thinking it's a delta thing (and now omicron), but for the first year of this whole thing I didn't know anybody or even hear of anybody who got seriously ill. I saw the fatality numbers rising, but it was people outside my social sphere. Over the past six months, I've been hearing more and more about it hitting on a second-order basis, where friends of mine know people personally who were seriously ill. I think maybe alpha was really hitting the older vulnerable population hard and I don't know many people like that, whereas delta has been having an impact on a more broad age range.
[Reply]
Monticore 04:24 PM 12-08-2021
Originally Posted by Chris Meck:
It seems pretty clear, doesn't it?
It seems even more clear when you factor in that only the vaccinated are aloud into high risk indoor environments (work/restaurants/arenas/movie theatres ) .
[Reply]
'Hamas' Jenkins 05:26 PM 12-08-2021
A study in Israel following 843,000 participants over 50 years old demonstrated a 90-percent reduction in mortality for booster recipients. It was published in NEJM today.
[Reply]
Donger 05:29 PM 12-08-2021
Originally Posted by 'Hamas' Jenkins:
A study in Israel following 843,000 participants over 50 years old demonstrated a 90-percent reduction in mortality for booster recipients. It was published in NEJM today.
Link:

https://www.nejm.org/doi/full/10.105...=featured_home

and another published today:

Protection against Covid-19 by BNT162b2 Booster across Age Groups

https://www.nejm.org/doi/full/10.105...=featured_home
[Reply]
TimBone 05:44 PM 12-08-2021
Originally Posted by OnTheWarpath15:
Update: He's not getting better, and it's likely he goes on a vent soon. So likely that the doc bent some rules and allowed myself and my sisters to visit this morning. Mom still has two days of quarantine before she can go.

I know this might be skirting - or flat blowing over the line - so if I'm in the wrong here, just delete the rest of this mods, but...

This all could have been avoided, but like so many others, he thought information from Facebook/The Internet carries more weight than from fucking professionals.

I hope those of you who are vaxxed and reading this realize how important getting those shots were to you and your families.

And I hope those of you who aren't vaxxed (and can be safely) will reconsider. My stepdad realizes now that he made a huge mistake, and now it's too late.

Don't do this to your families. Get the goddamn shots. Please.
Man....Sorry to hear about all of this, OTWP. His condition, falling prey to the misinformation...all of it is just terrible.
[Reply]
Bugeater 06:08 PM 12-08-2021
Originally Posted by Rain Man:
I'm thinking it's a delta thing (and now omicron), but for the first year of this whole thing I didn't know anybody or even hear of anybody who got seriously ill. I saw the fatality numbers rising, but it was people outside my social sphere. Over the past six months, I've been hearing more and more about it hitting on a second-order basis, where friends of mine know people personally who were seriously ill. I think maybe alpha was really hitting the older vulnerable population hard and I don't know many people like that, whereas delta has been having an impact on a more broad age range.
I'll go with that, because my first thought was what we all stopped doing over the summer...but that probably isn't it at all....YOU SHUT UP DONGER, THOSE STUPID MASKS DON'T WORK ANYWAY!
[Reply]
Chiefnj2 06:10 PM 12-08-2021
Originally Posted by Donger:
Link:

https://www.nejm.org/doi/full/10.105...=featured_home

and another published today:

Protection against Covid-19 by BNT162b2 Booster across Age Groups

https://www.nejm.org/doi/full/10.105...=featured_home
I don't think there is much debate that the vaccine helps against severe illness. The question is how long it lasts - even the booster. The new question is how does omicron change everything?
[Reply]
Donger 06:19 PM 12-08-2021
Originally Posted by Chiefnj2:
I don't think there is much debate that the vaccine helps against severe illness. The question is how long it lasts - even the booster. The new question is how does omicron change everything?
I would guess that it will last at least six months, but I haven't seen any studies on that. Since Israel was the first to go full out with the second booster, maybe we'll learn from them.

Nothing definitive yet on Omicron, but I haven't heard of a single fatality recorded from that variant yet, vaccinated/previous infection or not. Has anyone else? I realize that it's pretty new to the "game."
[Reply]
Donger 06:28 PM 12-08-2021
I read this over lunch. It's quite preliminary and has a small sample size, so please keep that in mind:

Studies suggest sharp drop in vaccine protection vs. omicron — yet cause for optimism

https://www.npr.org/sections/goatsan...se-for-optimis

With the omicron variant continuing to spread in a number of countries, including the U.S., scientists have been anxiously awaiting data to answer this question: How well will the vaccines work against this new variant?

On Tuesday night and Wednesday morning, scientists in South Africa and Germany released preliminary results from two small studies that begin to provide answers.

The studies haven't been peer-reviewed. But together, their data strongly suggest the vaccines will be much less effective at stopping infections from the omicron variant but will still likely offer protection against severe disease. The study in Germany also indicates that a third shot, or a booster, will partially recover the effectiveness of the vaccines, at least for a few months.

In the South African study, researchers at the Africa Health Research Institute took blood from about a dozen people who had been vaccinated with two shots of the Pfizer vaccine and looked to see how well their antibodies kill the virus. In the experiment, everyone's antibodies were able to neutralize an earlier version of the virus quite well.

But against omicron, that ability dropped dramatically. On average, the antibodies were 40 times less potent against omicron than against the variant circulating in the summer of 2020.

And that's a lot. "It's astonishing ... in terms of the reduction," says Pei-Yong Shi, a virologist at the University of Texas Medical Branch at Galveston who has been doing similar experiments to determine the effectiveness of the Pfizer vaccine against the coronavirus.

"We seem to see a drastic reduction in neutralizing activity, far more than with previous variants," virologist Florian Krammer, who's at the Icahn School of Medicine at Mount Sinai, wrote on Twitter. "Little activity was left in vaccinated individuals."

These findings confirm what scientists have been predicting since omicron was first detected several weeks ago. The virus contains many mutations already known to weaken the power of the antibodies made by the immune system.

Based on the results of this preliminary study, scientists say it's likely we'll see a lot more breakthrough infections with the omicron variant. And South Africa is reporting a lot of reinfections.

But the news isn't all dire. The vaccine isn't just about protecting against infections. It's also about protecting against severe disease and death. And there's reason to believe the vaccines will still do that, even with the omicron variant. Most of the people in the South African experiment did retain some ability to kill the virus. And scientists say even just a little bit of antibody activity can be enough to prevent someone from ending up in the hospital.

Also the immune system has other tools besides antibodies that can ward off severe disease. In particular, the T cells can clear out the virus after an infection. And scientists think those may hold up better against omicron than antibodies will.

On top of all that, the study from Germany shows that a third booster shot, with either the Pfizer or Moderna vaccines, increases the neutralizing ability of the antibodies to levels seen with the delta variant, at least for several weeks after the booster.

In that study, researchers at the Goethe University in Frankfurt looked at antibody potency against omicron and delta a half-month and three months after a third booster. In the short term, the antibody potency jumped up to the levels seen with delta in about half of the people. But after three months, most people's antibodies had declined to the level seen without the booster.

The vaccine manufacturer Pfizer also released a press statement Wednesday supporting these new findings.

"Preliminary neutralisation studies indicate that 2 doses of vaccines may not be sufficient to prevent *infection* w/ omicron (not severe disease), but regular boosters will help restore this decline to an extent," Dr. Muge Cevik, who's an infectious disease researcher at the University of St. Andrews, wrote on Twitter.
[Reply]
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