There is only weak evidence supporting ketamine's use (whether infusion or intranasal) in depression. Spravato isn't novel; it's just the S-enantiomer of ketamine with a longer half-life [Reply]
Law enforcement officials revealed they are launching a criminal investigation into the death of actor Matthew Perry.
Perry was found unresponsive at his Pacific Palisades home on Oct. 28, 2023. Following an autopsy, the Los Angeles County Department of Medical Examiner revealed in December the “Friends” actor died from “acute effects of ketamine.”
Now, the LAPD tells KTLA 5 News that they’re working with the Drug Enforcement Administration and the United States Postal Inspection Service to find out how and why the actor had so much of the substance in his system when he passed away.
TMZ first reported about the investigation early Tuesday morning.
“There were trace amounts of ketamine detected in the stomach contents,” the autopsy report stated. “He was reported to be receiving ketamine infusion therapy for depression and anxiety.”
Per the report, Perry’s last known treatment was one-and-a-half weeks before his death and the ketamine that was in his system when he died “could not be from that infusion therapy, since ketamine’s half-life is three to four hours, or less.” [Reply]
