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Nzoner's Game Room>***NON-POLITICAL COVID-19 Discussion Thread***
JakeF 10:28 PM 02-26-2020
A couple of reminders...

Originally Posted by Bwana:
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
Originally Posted by Dartgod:
People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

[Reply]
RustShack 03:34 PM 05-17-2020
I haven’t followed too closely lately. What’s the plan when we open up and in 2-4 weeks after it blows up again, close it back down or just let nature take its course but save the rich?
[Reply]
Demonpenz 03:42 PM 05-17-2020
Originally Posted by RustShack:
I haven’t followed too closely lately. What’s the plan when we open up and in 2-4 weeks after it blows up again, close it back down or just let nature take its course but save the rich?
it isn't going to blow up again. We are bored of it.
[Reply]
jdubya 03:42 PM 05-17-2020
Originally Posted by RustShack:
I haven’t followed too closely lately. What’s the plan when we open up and in 2-4 weeks after it blows up again, close it back down or just let nature take its course but save the rich?
I like rich people better than poor people so definitely save the rich



:-)
[Reply]
KCUnited 04:00 PM 05-17-2020
Covid numbers down on Sunday's as it reviews tax returns and strategizes for the week.
[Reply]
limested 04:01 PM 05-17-2020
Originally Posted by AustinChief:
Wtf are you talking about? We are talking about what numbers show whether or not Texas's reopening is causing a spike in Covid cases. The raw number of cases confirmed by testing is not a good indicator because of the increase in testing. Deaths in the other hand(given a lag time) are a much better indicator.

Your misleading fear mongering comment has zero to do with what we were discussing. If you choose to defend your comment please provide specific data and research on how many people as a percentage have proven permanent damage due to Covid-19. Make sure it is broken down by age please. Not sure how much I'm supposed to care about a 98 year old with "permanent" damage.

Sent from my moto g(7) power using Tapatalk
So explain how deaths is more accurate when all the people that claim things aren’t as serious as portrayed use the excuse that deaths are over and misreported as being due to Covid19?
[Reply]
'Hamas' Jenkins 04:35 PM 05-17-2020
Originally Posted by AustinChief:
Wtf are you talking about? We are talking about what numbers show whether or not Texas's reopening is causing a spike in Covid cases. The raw number of cases confirmed by testing is not a good indicator because of the increase in testing. Deaths in the other hand(given a lag time) are a much better indicator.

Your misleading fear mongering comment has zero to do with what we were discussing. If you choose to defend your comment please provide specific data and research on how many people as a percentage have proven permanent damage due to Covid-19. Make sure it is broken down by age please. Not sure how much I'm supposed to care about a 98 year old with "permanent" damage.

Sent from my moto g(7) power using Tapatalk
It's a worthwhile question with muddy data at this point. Most of the analysis are cohort studies from patients that have been hospitalized, and thus have severe disease. Also, patients can present with multiple comorbidities.

As one would expect, older patients tend to have more severe effects, but it's also early to assume permanent dysfunction. However, there are markers of damage in a number of bodily systems

Cardiac injury in Wuhan: 19.7% of hospitalized patients had elevated cardiac enzymes indicative of myocardial damage. Those patients were older (mean age 74) than those without (60). Roughly half of patients with cardiac injury survived.

https://jamanetwork.com/journals/jam...?resultClick=1


Neurological manifestations in Wuhan: Approximately 36% of admitted patients were found to have some degree of CNS, skeletal, or PNS manifestation. Again, severity of illness and age were correlated more strongly with the likelihood of these issues. As this is a broad constellation of issues, it's important to delineate specific examples: acute cerebrovascular disease, like an ischemic stroke, happened in 2.8% of patients, whereas skeletal muscle injury happened in around 11% of patients, and alterations in taste and smell were closer to 5-6%

https://jamanetwork.com/journals/jam...rticle/2764549


Lung Damage:

SARS and MERS caused permanent lung damage in around 1/3 of cases. It's hard to know exact numbers for COVID-19 at this point, but a substantial number of discharged patients showed indications of lung damage on CT.

https://pubs.rsna.org/doi/full/10.11...iol.2020200843

94% (66/70) of patients who were discharged from hospital at the end of the study still had mild to substantial residual lung abnormalities on their last CT scans. The main pattern of those lung abnormalities was ground-glass opacity. A most recent publication reported 4 discharged cases who had positive SARS-CoV-2 RT-PCR results again 5-13 days after discharging(22). Thus, follow-up monitoring of patients might still be necessary

GGOs can resolve and they can be indicative of long-term damage to the alveoli. It's too soon to know.

Of course, more severe patients develop ARDS, and although many survive, ARDS in ICU patients leads to longterm cognitive impairment approximately 1/5th of the time (Paywalled for you, most likely: https://journals.lww.com/ccmjournal/...s__Risk.8.aspx)

Clotting Disorders:

Patients with more severe disease will be more likely to present with a coagulopathy. Around 30% of hospitalized patients in France were found to have a PE if they weren't in ICU, compared to 72% of those who were (sample sizes were low; n=32 for ICU, n=72 for not, but the differences are enough for a p < 0.001) Those that have a DVT, PE, or stroke will need to remain on anticoagulant therapy for at least six months afterwards, which carries its own burdens and risks.

https://pubs.rsna.org/doi/10.1148/radiol.2020201561

As for the ultimate breakdown on all subgroup analyses, that will take time, but it is clear that this is a disease that attacks multiple organ systems, often through coagulopathies. As one would expect with any other disease, the older and sicker you are, the worse your prognosis, but this is not merely an issue affecting the elderly.
[Reply]
Bowser 04:40 PM 05-17-2020
Apparently antibody tests are showing that this thing is spread out way more than initially thought -

https://justthenews.com/politics-pol...fTW5U.facebook
[Reply]
Titty Meat 04:43 PM 05-17-2020
Originally Posted by Bowser:
Apparently antibody tests are showing that this thing is spread out way more than initially thought -

https://justthenews.com/politics-pol...fTW5U.facebook
Do you have a source that's not right wing bias?
[Reply]
'Hamas' Jenkins 04:45 PM 05-17-2020
Originally Posted by Bowser:
Apparently antibody tests are showing that this thing is spread out way more than initially thought -

https://justthenews.com/politics-pol...fTW5U.facebook
Not really. They're mixing several different antibody studies, some of them using older tests with false positive rates above 50%, with newer, more specific tests, and flu counts are always estimated, which is why they are often 6-10 times higher than reported flu deaths, which does precisely the opposite of what the author claims.

A study posted this week in Spain, which is one of the hardest hit countries in Europe, showed a total seroprevalance of 5% with no region higher than 14%. This extrapolated to a total IFR of 0.7%, seven times higher than the flu.

*Note that I backdated deaths to the point where the study began, so in reality the IFR is likely higher. Many other estimates have it around 1.15%*
[Reply]
jdubya 04:49 PM 05-17-2020
Originally Posted by 'Hamas' Jenkins:
Not really. They're mixing several different antibody studies, some of them using older tests with false positive rates above 50%, with newer, more specific tests, and flu counts are always estimated, which is why they are often 6-10 times higher than reported flu deaths, which does precisely the opposite of what the author claims.

A study posted this week in Spain, which is one of the hardest hit countries in Europe, showed a total seroprevalance of 5% with no region higher than 14%. This extrapolated to a total IFR of 0.7%, seven times higher than the flu.
Are the antibody tests today fairly accurate?
[Reply]
Chief Roundup 05:06 PM 05-17-2020
Originally Posted by ghak99:
So the Governor himself issued regulations restricting interstate travel enforced via fines paid to the state? Do you know what law he used to back this restriction?

I hope someone jumped all over this.
It was about people coming into the state for recreation. It required those that came into the state to notify the Arkansas Department of Health and for them to isolate/quarantine for 14 days. No beyond that I don't know. This stuff was talked about on the news though. I am sure that this happened in a lot of other places across the country.

This is part of what he did. It was an executive order.
https://www.ky3.com/content/news/Gov...569382031.html
[Reply]
Bowser 05:07 PM 05-17-2020
Originally Posted by Titty Meat:
Do you have a source that's not right wing bias?
Do you have the ability to read a story and not see partisanship?
[Reply]
petegz28 05:12 PM 05-17-2020
Originally Posted by Bowser:
Do you have the ability to read a story and not see partisanship?
I read the article and didn't see any politics mentioned one way or the other. But then again think about who you are talking too. Why read something that may go against your predetermined conclusion when you can use a site (that I have never heard of) as a reason not to read it?
[Reply]
Titty Meat 05:26 PM 05-17-2020
Originally Posted by Bowser:
Do you have the ability to read a story and not see partisanship?
That site is notorious for fake news and no surprise mins after you posting it Hamas shot it down. Quit posting fake shit you're a mod you should know better.
[Reply]
'Hamas' Jenkins 05:27 PM 05-17-2020
Originally Posted by jdubya:
Are the antibody tests today fairly accurate?
Depends on the test. Most of the early tests (like the ones used on the Boston and Santa Clara examples listed in Bowser's link) had extremely poor specificity which rendered them a coinflip at best and led to a vast overestimation of the number of infections and a complete misrepresentation of the fatality rate (claiming it was much lower than reality).

Some of the newer tests that have been verified by outside parties have much better specificity levels, but it needs to be above 99.5% to have clinical utility in this environment.
[Reply]
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