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Nzoner's Game Room>***NON-POLITICAL COVID-19 Discussion Thread***
JakeF 10:28 PM 02-26-2020
A couple of reminders...

Originally Posted by Bwana:
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
Originally Posted by Dartgod:
People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

[Reply]
Monticore 09:04 AM 12-19-2020
Originally Posted by stevieray:
That was one of the things that always stuck out.

You have to PRESUME you have it and have to PRESUME you are asymptomatic, yet are still "contagious"
They have known this for a while , pre symptomatic spread ( infected but no symptoms yet) is the main issue of a symptomatic spread , or very mild or weird symptoms for a respiratory disease ( diarrhea) .
[Reply]
MahomesMagic 09:18 AM 12-19-2020
Question is will Facebook fact checkers still rate this as false information?!
[Reply]
O.city 09:29 AM 12-19-2020
Originally Posted by stevieray:
That was one of the things that always stuck out.

You have to PRESUME you have it and have to PRESUME you are asymptomatic, yet are still "contagious"
By the time you show symptoms, you’ve been infectious for a solid 48 hours.
[Reply]
stevieray 09:37 AM 12-19-2020
Originally Posted by O.city:
By the time you show symptoms, you’ve been infectious for a solid 48 hours.
IF you show symptoms.
[Reply]
Monticore 09:56 AM 12-19-2020
Originally Posted by stevieray:
IF you show symptoms.
Unless you can predict the future , you can at least see the dilemma right?
[Reply]
petegz28 10:13 AM 12-19-2020
Originally Posted by Monticore:
Unless you can predict the future , you can at least see the dilemma right?
People can't perpetually live their lives assuming they are sick as well.....
[Reply]
Rain Man 11:32 AM 12-19-2020
Originally Posted by O.city:
The number one risk factor for this seems to be age. Last couple things I've read had obesity not quite at the risk factor level they initially thought.

It's definitely a risk factor for various other issues and a big problem, causes a huge bog on health care and health care costs yearly.

I'm not sure the solution.
I've been trying to lower my age count for years, but nothing seems to work.
[Reply]
suzzer99 11:38 AM 12-19-2020
Originally Posted by Monticore:
They have known this for a while , pre symptomatic spread ( infected but no symptoms yet) is the main issue of a symptomatic spread , or very mild or weird symptoms for a respiratory disease ( diarrhea) .
My friend thought it was just allergies for the first few days. During that time she gave it to her roommate. Then they both got pretty sick. The line between asymptomatic/presymptomatic and symptomatic is very fuzzy.
[Reply]
Donger 11:46 AM 12-19-2020
FWIW:

London (CNN)Parts of Britain will go back into lockdown during Christmas after a newly identified strain of Covid-19 proved to spread more quickly than previous strains of the virus.

UK Prime Minister Boris Johnson on Saturday announced a series of stricter coronavirus restrictions, tightening rules around household mixing that were due to be relaxed over Christmas in London and southeast England.

The PM broke the news Saturday that London and the southeast of England, where cases are surging, will go into Tier 4 restrictions, similar to a lockdown, on Sunday.

"The spread is being driven by the new variant of the virus," Johnson said in a hastily called press conference. "It appears to spread more easily and may be up to 70% more transmissable than the earlier strain."
[Reply]
stevieray 11:48 AM 12-19-2020
Originally Posted by Donger:
FWIW:

London (CNN)Parts of Britain will go back into lockdown during Christmas after a newly identified strain of Covid-19 proved to spread more quickly than previous strains of the virus.

UK Prime Minister Boris Johnson on Saturday announced a series of stricter coronavirus restrictions, tightening rules around household mixing that were due to be relaxed over Christmas in London and southeast England.

The PM broke the news Saturday that London and the southeast of England, where cases are surging, will go into Tier 4 restrictions, similar to a lockdown, on Sunday.

"The spread is being driven by the new variant of the virus," Johnson said in a hastily called press conference. "It appears to spread more easily and may be up to 70% more transmissable than the earlier strain."
And so it begins...
[Reply]
notorious 11:52 AM 12-19-2020
Originally Posted by stevieray:
And so it begins...

At this rate it will never end.
[Reply]
stevieray 11:57 AM 12-19-2020
Originally Posted by notorious:
At this rate it will never end.
I think that's the plan.
[Reply]
Donger 11:59 AM 12-19-2020
Originally Posted by notorious:
At this rate it will never end.
Of course it will. It's not seasonal influenza, which doesn't go away.
[Reply]
MahomesMagic 12:02 PM 12-19-2020
https://www.gisaid.org/references/gi...-vui-20201201/


UK reports new variant, termed VUI 202012/01
The United Kingdom reported a new variant, termed VUI 202012/01 (Variant Under Investigation, year 2020, month 12, variant 01). It was defined by multiple spike protein mutations (deletion 69-70, deletion 144-145, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H). There are currently 24,746 viruses from the UK in GISAID EpiCoV with a collection date since 1. November. A small fraction of them, about 6% (all from clade GR) share several of these mutations. Based on evaluation of effect on virus structure and function, the most relevant might be N501Y (orange in Figure; host receptor and antibody binding, also reported at gisaid.org/spike) and the deletions (cyan in Figure) in positions contributing to potential spike surface variation (Y145del is where some antibodies like neutralizing 4A8 bind).

The other mutations (blue in Figure) are further down the structure and their effect is less clear. There is also an early NS8 Q27stop codon in these strains which could be relevant as ORF8 deletions have been seen before for this virus (including in Singapore, notably resulting in attenuation). As seen on many occasions before, mutations are naturally expected for viruses and are most often simply neutral regional markers useful for contact tracing. The mutations seen have rarely been affecting viral fitness and almost never affect clinical outcome but the detailed effects of these mutations remain to be determined fully.
[Reply]
MahomesMagic 12:08 PM 12-19-2020

1) THREAD - Why the new SARS-CoV-2 UK variant is NOT a new strain.

Unfortunately the way this recent development has been reported has upset a lot in the scientific community. It scares the public rather than inform them. That's where we come in. pic.twitter.com/Z525j0NjdG

— Simply Biochemistry (@SimplyBiochem) December 15, 2020


A new strain of COVID-19 would have to be so different from the original that your immune system's training through vaccination or getting it previously would no longer be useful.

The new spike protein would have to differ so much from the original.

But is this the case? No.

This mutation is called N501Y. There is currently NO evidence that this variant, or any other, significantly affects the immune-trained response or increases infectiousness, rate of transmission or severity of infection.

So why are people panicking? Misreporting.

Most people will read 'New COVID-19 strain' on a headline and think the worst. At the moment, researchers are closely monitoring mutations, but there is no evidence of concern yet to report.

What could be causing the prevalence of this variant?

Chance. The prevalence of this variant could be due to the other variants reaching a state of 'Zero COVID' during lockdowns. Superspreaders could have then been responsible for this variant taking the lead.

Whilst prevalence can suggest that it does have an evolutionary advantage, correlation does not equal causation!

For now, we can be confident that vaccines will work on this new variant, and we can still expect some semblance of normality in 2021. Stay hopeful!
[Reply]
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