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Nzoner's Game Room>***NON-POLITICAL COVID-19 Discussion Thread***
JakeF 10:28 PM 02-26-2020
A couple of reminders...

Originally Posted by Bwana:
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
Originally Posted by Dartgod:
People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

[Reply]
TLO 06:02 PM 07-08-2020
Coronavirus may have arrived in the US from China, but most of the spread was domestic, model suggests
From CNN’s Naomi Thomas


Coronavirus was probably spreading widely across the US in February, new modeling data suggests, and it only took a few imported cases from other countries to set off rapid spread inside the borders.

While direct imports from China and other countries may have been responsible for the early introduction of Covid-19 to the US, most spread was state to state, researchers led by a team at Northeastern University in Boston reported.

“We estimate widespread community transmission of SARS-CoV-2 in February, 2020,” a team led by Northeastern’s Laboratory for the Modeling of Biological and Socio-technical Systems wrote on MedRxiv, a pre-print server. Their work has not been peer-reviewed.

“Our results indicate that many states were seeded from domestic sources rather than international,” they wrote. “For most of the continental states, the largest contribution of imported infections arrived through domestic travel flows.”
The US announced restrictions on travel from China on Jan. 31. The researchers say their modeling study suggests the restrictions came far too late.

“Importations from mainland China may be relevant in seeding the epidemic in January, but then play a small role in the COVID-19 expansion in the US because of the travel restrictions imposed to/from mainland China after January 23, 2020,” they wrote.

“Domestic sources account for 85% of the virus introductions in Nebraska, 86% in New Mexico, 86% in Arkansas, and 95% in North Dakota,” they added.
The model jibes with evidence from several studies that suggest there were already a significant number of infections in the US by the time the travel restrictions were announced on January 31, the researchers wrote.
[Reply]
O.city 06:11 PM 07-08-2020
https://twitter.com/psampathkumarmd/...547269122?s=21

Good thread here
[Reply]
O.city 06:16 PM 07-08-2020
Originally Posted by TLO:
Speaking of immunity - has anyone seen anything on how long antibodies/t-cell response, etc, provides protection? Last I knew they still weren't sure.
T cell mediated would be a while.

People are getting hung up on antibodies waning. They always do. That’s why we have memory B cells
[Reply]
TLO 06:17 PM 07-08-2020
Originally Posted by O.city:
https://twitter.com/psampathkumarmd/...547269122?s=21

Good thread here
Speaking of - I found this on Reddit earlier today.

https://www.nature.com/articles/s41577-020-0389-z
[Reply]
lewdog 06:54 PM 07-08-2020
How does herd immunity work if they’re showing antibody disappearance between 1-4 months for many people in cross sectional studies that also show you can get reinfected?
[Reply]
O.city 06:57 PM 07-08-2020
Originally Posted by lewdog:
How does herd immunity work if they’re showing antibody disappearance between 1-4 months for many people in cross sectional studies that also show you can get reinfected?
We don’t always keep making antibodies for things once we’ve cleared them. We have memory cells that will ramp up and make them if we encounter said antigen again.

Up to this point, there hasn’t been proven reinfection that I’ve seen or read. That would go against everything we have so far in virology for the most part. Immunity may wane but I would imagine it’ll last atleast a year or so and even then you may be able to get it again but it would be very mild
[Reply]
lewdog 07:00 PM 07-08-2020
Originally Posted by O.city:
We don’t always keep making antibodies for things once we’ve cleared them. We have memory cells that will ramp up and make them if we encounter said antigen again.

Up to this point, there hasn’t been proven reinfection that I’ve seen or read. That would go against everything we have so far in virology for the most part. Immunity may wane but I would imagine it’ll last atleast a year or so and even then you may be able to get it again but it would be very mild
https://www.medrxiv.org/content/10.1....11.20086439v2
[Reply]
Chief Pagan 07:06 PM 07-08-2020
Originally Posted by chiefzilla999:
We need to build up the herd and those that wish to isolate may.
If you take that approach, the economy will be depressed for a long time.

Sure, some people will go back to normal, but many won't.

Airline travel was never shut down and customers are way down. Vegas opened up and casinos are empty enough they aren't making money. Travel and jobs related to it are, or at least were, a big part of the economy.
[Reply]
O.city 07:07 PM 07-08-2020
Originally Posted by lewdog:
https://www.medrxiv.org/content/10.1....11.20086439v2
Interesting
[Reply]
Chief Roundup 07:09 PM 07-08-2020
Originally Posted by lewdog:
How does herd immunity work if they’re showing antibody disappearance between 1-4 months for many people in cross sectional studies that also show you can get reinfected?
Originally Posted by O.city:
We don’t always keep making antibodies for things once we’ve cleared them. We have memory cells that will ramp up and make them if we encounter said antigen again.

Up to this point, there hasn’t been proven reinfection that I’ve seen or read. That would go against everything we have so far in virology for the most part. Immunity may wane but I would imagine it’ll last atleast a year or so and even then you may be able to get it again but it would be very mild
I have wondered about this stuff also. Since Covid-19 is a Coronavirus just like Flu A and Flu B we do not have immunity and can be reinfected what seems fairly soon what makes Covid-19 different?
[Reply]
O.city 07:12 PM 07-08-2020
Originally Posted by Chief Roundup:
I have wondered about this stuff also. Since Covid-19 is a Coronavirus just like Flu A and Flu B we do not have immunity and can be reinfected what seems fairly soon what makes Covid-19 different?
Flu a and b aren’t corona viruses. There are 3 or 4 corona viruses in circulation regularly that do cause colds but Influenza is Different
[Reply]
Chief Roundup 07:22 PM 07-08-2020
Originally Posted by O.city:
Flu a and b aren’t corona viruses. There are 3 or 4 corona viruses in circulation regularly that do cause colds but Influenza is Different
Oh ok then those are Rhinoviruses while the common cold is the coronavirus that there is no immunity to that I am thinking about.
[Reply]
BryanBusby 07:30 PM 07-08-2020
Originally Posted by eDave:
$2/hr. 1/2 clientele. Risk of getting shut down again and refiling (and waiting, and waiting). All for a shot at getting sick and dying. No thanks.
Once you clear that first hurdle you've got a window that's open for multiple months to claim unemployment without any additional waiting week.

So you could in theory go back to work shortly, get laid off and directly go back to drawing unemployment.
[Reply]
lewdog 07:31 PM 07-08-2020
Originally Posted by O.city:
Interesting
Interesting.....as in possibly not good.
[Reply]
Kidd Lex 07:32 PM 07-08-2020
Originally Posted by Chief Roundup:
Oh ok then those are Rhinoviruses while the common cold is the coronavirus that there is no immunity to that I am thinking about.
You do get immunity to the common cold, but it usually only lasts 12-18 months. I’d guess Covid-19 is similar to SARS in that the worse the infection the longer the immunity. For asymptomatic people that’s probably only 12-18 months, but also means a reinfection would likely be mild as well. Vaccine will help, but it’s going to be like the Manhattan project trying to vaccinate the entire world before immunity wanes. Will be interesting, but the Science is still developing. One cool thing I read is that the Oxford vaccine is helping people develop three times the amount of antibodies as a typical community spread Covid case. I’d assume one of these vaccines is going to provide a response akin to 3-5 plus years of immunity. That would be enough to eradicate this damn virus.
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