Originally Posted by Bwana:
Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.
Originally Posted by Dartgod:
People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.
We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.
Thanks!
Click here for the original OP:
Spoiler!
Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.
California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM
The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.
“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”
The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.
The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”
Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.
The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.
The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.
A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.
Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.
“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”
It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.
“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”
On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.
“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”
According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.
More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.
But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.
“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”
CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.
Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.
“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”
Hamas and Dane are 2 of the most respected posters on the site and both don’t seem to give any validity to reports of certain drugs being highly effective in battling the covid19. [Reply]
Originally Posted by 'Hamas' Jenkins:
Well, normally we make evidence-based medical decisions upon the results of randomized clinical trials and not tweets about the claims of success from a single practitioner.
Whether you are a Sunshine Pumper, Debbie Downer, or somewhere in between on these treatments, I think most of us can agree that the verdict on many of these treatments will be decided long before the clinical papers are printed. [Reply]
Originally Posted by kgrund:
Whether you are a Sunshine Pumper, Debbie Downer, or somewhere in between on these treatments, I think most of us can agree that the verdict on many of these treatments will be decided long before the clinical papers are printed.
Just like the CDC got in the way with testing, the FDA is getting in the way with treatment.
Ignore both in this instance and go around. [Reply]
Originally Posted by Titty Meat:
So now were settling science with tweets and message board opinions? :-)
or accepting other countries findings because the FDA is dragging its feet like the CDC did with testing..... The evidence keeps building, but by all means wait for the FDA. [Reply]
It's promising if the drugs are doing good things, but scientific testing takes longer than that to get a better overall picture. If these people all relapse, keel over, or develop cancer from these treatments then we don't have much to celebrate now do we? Extreme possibilities I know but anything is possible. [Reply]
Originally Posted by Gravedigger:
It's promising if the drugs are doing good things, but scientific testing takes longer than that to get a better overall picture. If these people all relapse, keel over, or develop cancer from these treatments then we don't have much to celebrate now do we? Extreme possibilities I know but anything is possible.
no developing cancer from a drug in use for 70 years is not possible...... [Reply]
Originally Posted by BleedingRed:
or accepting other countries findings because the FDA is dragging its feet like the CDC did with testing..... The evidence keeps building, but by all means wait for the FDA.
Didn’t the other countries test have a high false positive or something?
Yeah, we need to do our own testing to make sure it’s safe and it works [Reply]
Originally Posted by BossChief:
This is very interesting.
Hamas and Dane are 2 of the most respected posters on the site and both don’t seem to give any validity to reports of certain drugs being highly effective in battling the covid19.
I wouldn't say that I don't give any validity to them; what I'm saying is that, as someone who was trained in the evaluation of evidence to make medical decisions, there is not sufficient evidence to state that HCQ+Azithromycin is a panacea.
It may well work. The mechanism of action (raising intracellular pH to reduce endocytosis of the virus) makes sense in a vacuum. However, and I've said this numerous times before--for every small molecule drug that is approved there are thousands--literally thousands--that fail. In vitro success does not mean in vivo success. The human body is a much different machine than even other mammals, and certainly test tubes.
I'll use an extreme example: they've known about something that costs pennies that can inactivate every known virus for decades. Sodium hypochlorite in water.
Well, why can't you use it: because pumping bleach into your veins will kill you.
Every drug is a poison. The trick is finding a poison that kills the pathogen before it begins harming (or kills) the host. You also need to make sure that it has appropriate absorption and distribution to get where you need to it go and that it is metabolized and eliminated in a manner that avoids toxicity.
People need to understand that sometimes the best answer to a question is, "I don't know." It's difficult to hear with so much information to be accessed, but the true answer right now is that we don't know. You can say that it will be effective or that it won't, but at this point, you're really just betting on sports futures, and that's not how medical decisions should be made. [Reply]
There is no money to be made advancing these drug treatments rapidly to registration.
If you are a University you desire complex multi level long term trials involving scads of observations...
On the other hand, the drugs have been proven safe for people to take so we don't really need data on if its toxic to people, and the side effects are well known.
What we don't know to a gnats ass of total accuracy is what does it do when taken by someone with this virus. And in truth that will be important to some researchers and will no doubt be studied for years.
In the meantime, it would seem logical and practical to move forward and use what information can be developed with a goal of full use if the product is working.
To require the usual battery of protocols and testing required for a new discovery compound is absurd. There will be so little profit in this stuff since its all generic, no one will pay for those trials anyway, and we damn sure don't need the feds shoveling more money into Universities to study things to death at high costs. [Reply]
Originally Posted by 'Hamas' Jenkins:
You guys really need to leave this to the professionals, because you're arguing about metrics that you don't understand and it is both harmful and incredibly arrogant.
Originally Posted by BleedingRed:
or accepting other countries findings because the FDA is dragging its feet like the CDC did with testing..... The evidence keeps building, but by all means wait for the FDA.
Let the scientist and medical professionals do their thing. This kind of stuff is above about 99% of the folks on this board. [Reply]
Originally Posted by Titty Meat:
Let the scientist and medical professionals do their thing. This kind of stuff is above about 99% of the folks on this board.
thats the thing Medical Professionals are doing their thing. Where is the update from NY's trial? [Reply]
